Integrated Multiomic Analysis Reveals the High-Fat Diet Induced Activation of the MAPK Signaling and Inflammation Associated Metabolic Cascades via Histone Modification in Adipose Tissues

BackgroundThe number of diet induced obese population is increasing every year, and the incidence of type 2 diabetes is also on fr3781 the rise.Histone methylation and acetylation have been shown to be associated with lipogenesis and obesity by manipulating gene expression via the formation of repression or activation domains on chromosomes.Objecti

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A gigantic bizarre marine turtle (Testudines: Chelonioidea) from the Middle Campanian (Late Cretaceous) of South-western Europe

Abstract Marine turtles were common in the subtropical Upper Cretaceous epi-continental seas that once washed the coasts of the ancient European archipelago.But unlike its contemporaneous faunas from North America, in Europe no taxon surpassed the 1.5 m shell-length.Here, the remains of a new large marine turtle, Leviathanochelys aenigmatica gen.et

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Collusive and adversarial replication

I describe a game in which social ties between members of a research community may discourage prospective replicators from debunking papers that misreport results.Here, replication is an entrance decision, as a Replicator chooses whether or not to Replicate a given paper.A high level of social connectedness rt100 mini bike parts between members of

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